ABZ Science
The Structure, Function and Genetics of Z-DNA and Z-RNA
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In contrast to the common right-handed A- and B-conformations of RNA and DNA, their Z-conformations are left-handed. Starting with the crystallization of Z-DNA in 1979, biophysical and biochemical studies have yielded many unanticipated and fascinating insights into this class of higher energy nucleic acid conformations.
Recent discoveries of biological functions for Z-conformations have demonstrated important roles in immunity against infectious agents and cancers. More generally, research on Z-conformations underscore the impact of alternative RNA and DNA conformations in both normal cellular function and disease. They further emphasize that regulatory information is encoded by structure in addition to sequence.
The 'ABZ Meeting 2025' will be held on November 12!
The meeting will be held virtually (Zoom) on
November 12th, 2025
Tentative times:
8 am – 1 pm EDT (US Eastern Daylight)
5 am – 10 am PDT (Pacific Daylight)
1 pm – 6 pm GMT (Greenwich Mean)
9 pm (Nov 12th) – 2 am (Nov 13th) SGT (Singapore)
10 pm (Nov 12th) – 3 am (Nov 13th) JST (Japan Standard)
Participation is free of charge
Program:
As we have done successfully since our inaugural meeting in 2021, we will feature speakers from many different fields to increase awareness of the many innovative approaches available to further advance the field. Our aim is to build community and to foster multidisciplinary collaborations.
Confirmed speakers:
Peter Dröge Nanyang Technological University Singapore
Yang Gao Rice University Houston
Ilias Georgakopoulos-Soares Pennsylvania State University /University of Texas at Austin
Jacki Heraud Farlow Hudson Institute of Medical Research, Melbourne
Huipeng Jiao Zhejiang University
Gianmaria Liccardi University of Cologne
Wei Mo Zhejiang University School of Medicine
Taisuke Nakahama Osaka University
We will also select speakers from submitted abstracts. Students and postdocs are also highly encouraged to apply. Abstract deadline is October 17.
Register and abstracts here
Questions to info@abz.bio
Past meetings:
Since our inaugural meeting in 2021, we have featured 69 speakers and >550 participants
ABZ Meeting 2022, second leg, September 7 (Asia)/September 6 (US)
ABZ Meeting 2022, first leg, May 25
For more information klick on the meetings
Contacts:
E-mail: info@abz.bio
Dr. Quentin Vicens
Department of Biology and Biochemistry, University of Houston
E-mail: qvicens@uh.edu
Dr. Beat Vögeli
Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora
E-mail: beat.vogeli@cuanschutz.edu
Dr. Alan Herbert
Discovery, InsideOutBio, Inc., Charlestown, MA, USA
E-mail: alan.herbert@insideoutbio.com
Dr. Karen Vasquez
University of Texas at Austin
E-mail: karen.vasquez@austin.utexas.edu
Dr. Yukio Kawahara
Osaka University
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